Evaluation of complete blood count, c-reactive protein, and lactate dehydrogenase in culturable and unculturable bacteremia for early diagnosis of sepsis

Bacteremia is a bacterial infection that enters the bloodstream. This study was designed to investigate if culture methods could detect of bloodstream and assess certain criteria for sepsis in culturable non-culturable blood samples from hospitalized patients, like C-reactive protein (CRP), lactate dehydrogenase (LDH), complete count (CBC). A total 100 patients with symptoms who resided Hilla City hospital were collected as well 25 healthy control group without disease or inflammation. Each sample divided into three containers; 2ml an EDTA tube CBC test, 3ml centrifuged CRP LDH 3-7ml brain heart infusion broth culture. The result showed 65 (65%) had abnormal tests, whereas only (25%) positive. There statistically significant difference between regarding all parameters CRP, LDH, white cell (WBC), lymphocyte (LYM) granulocyte (GRA) (P= 0.000). No association studied observed culture-positive culture-negative patients. Significant strong positive correlation WBC (r= 0.332) (p= 0.007), LYM GR) -0.983) 0.000), 0.257) 0.03), GRA 0.254) 0.04). Therefore, estimation WBC, granulocytes, lymphocytes count, values results may help early identification causative agent sepsis.